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Where can you buy Tramadol?

Based on the list of trade names per country, you can buy tramadol practically anywhere. However, it is a drug that should not be bought without a prescription, one that is written particularly for your case. So, it is best to buy Tramadol from your local pharmacy if possible.However, you can be sure to buy drugs in the best condition (not expired, genuine) from our US legal online Pharmacy. You may also ask questions from your local pharmacist if you are a little uncertain, especially when refilling your prescription.

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What is Tramadol?
Tramadol hydrochloride is an analgesic that works on the central nervous system to relieve moderate to slightly severe pain. Examples of brand names are Ultram and Tramal. (Further information here about brand and trade names of the drug from different countries of the world.) 

Tramadol has several applications, including the treatment of obvious painful conditions such as fibromyalgia and rheumatoid arthritis, as well as restless legs syndrome. The drug was developed in the late 1970s by the pharmaceutical company, Grünenthal GmbH.
Tramadol is an effective pain reliever when it comes to the treatment of intermediate, chronic pain caused by accidents, surgery and medical conditions. It is not as easily-abused as other analgesics but still poses a threat of being so.

With proper use, Tramadol should be able to provide effective pain relief. The drug is available to buy in several formulations and forms, under various trade or brand names. 
 Some people may be tempted to use Tramadol as a recreational drug because it is not detected in some commercial drug screening tests. 
In the Gaza Strip, Tramadol dependence is considered to be a major social problem. The Hamas government has actually actively attempted to cut off Tramadol supplies in the area. In April 2010, it set two million intercepted tablets on fire. These tablets were being smuggled into the strip.

Forms of the Medication

So what are the different forms of Tramadol that you can take? Here are those forms and their dosages:

Injection: This is available in 100mg dosages. It was marketed by the Grünenthal GmbH, which is the trademark owner of the original ‘Contramal,’ which is a Hungarian brand name of Tramadol. 

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The Tramadol form that can be injected is usually Tramadol hydrocholoride, which is marketed not only as a central nervous system drug but also plainly as hydrochloride salt. The tartrate for is rarely available, especially in the US.

Tramadol is available for both intravenous and/or intramuscular form of injection.  The solutions that are suitable for injection can be placed in analgesic pump format that can be controlled by the patient.

Injections are also in the form of preservative-free solutions that can be administered through various spinal routes, such as caudal, epidural and intrathecal.
Tramadol comes in sterile solutions for IM, IV and SC injection in ampules.

Oral Tablet: Tramadol is also available for oral administration. The most popular dosage unit is the 50 mg generic tablet. This tablet is manufactured not just by one company. It is often combined with APAP, which means paracetamol/acetaminophen, and distributed as the brand Ultracet. In this form, the dosage is smaller, at only 37.5 mg Tramadol because it is combined with 325 mg of APAP. 

Meanwhile, Tramadol HCl tablets, in 50 mg dosages, are being delivered by Akyma Pharmaceuticals under the generic name Ultram. Anyway, immediate release versions of the drug are available in several general preparations.

Extended-release Tramadol HCl or generic Ultram ER is available in bottles containing 200 mg tablets. The medication is also available in 100 and 300 mg strengths that should be taken once a day. It is commonly prescribed together with Tramadol-APAP (Ultracet). For breakthrough pain, it is combined with Ultram, Tramal or Rybix, which are regular immediate-release Tramadol HCl.

Tablets are available in not just extended-release forms but also in regular and chewable forms. They are also available in either low-residue and/or uncoated tablets, as well as effervescent tablets or powders. 

Suppositories: Tramadol also comes in suppository form. Suppositories are recommended for patients who cannot keep the drug in due to vomiting.

Liquids: The drug is also available in liquid form, whether with or without alcohol. Liquids are prepared for sub-lingual and oral administration. In this form, the medicine is available in phials and bottles, some of which have droppers or pumps like the ones used in liquid soaps.         

The problem with Tramadol in liquid form is that it has a characteristically unpleasant taste, one that is slightly bitter. Compared to codeine and morphine, however, the taste should be more manageable. Liquid preparations, however, can come with or without added flavour to improve the taste. 50 mg water-soluble tablets come with a strawberry flavor that is not limited to just one company. This is actually a means to distinguish the water-soluble tablet form of Tramadol from Mirtazapine sublingual tablets. The latter is always laced with orange flavor no matter which manufacturer produces it. This flavoring is considered standard for the particular medication.

Topical Form: Tramadol is also available in topical form. This means that you can buy the painkiller in several forms of topical gels, creams and other solutions that can be applied on the skin to relieve nerve pain. It is even available in rectal foam, skin plaster (otherwise known as transdermal patch) and concentrated retention enema. 

The form in which Tramadol comes affects the dosage that the patient is given. For example, Tramadol that is capped with APAP can only be taken to a maximum of eight tablets a day because each tablet has the strength of 37mg, to a total of 300 mg a day.

For oral use, on the other hand, the maximum dosage is 400 mg a day. 600 mg is the daily maximum for parenteral use. 

Take note though that there are manufacturers that advise lower maximum doses, based on their unique formulations. 

There are people who are advised lower dosages, such as those who are younger than 18 years old or older than 75 years old; those who are going through kidney or liver malfunctions and those who are taking SSRIs such as Prozac and Zoloft. 

No matter what the case is and no matter what the form of Tramadol is to be used, patients should always inform their doctors about every personal and medical history that they think will be relevant to the prescription: age, history of drugs and diseases, etc.

How does the drug work?

You already know that Tramadol is a synthetic pain reliever. So, it has been manufactured to relieve pain. The specifics of its mechanism of action is not known but is understood to be similar to that of morphine.

So, how does Tramadol do it? Like morphine, Tramadol binds the pain receptors, otherwise known as mu receptors or opioid receptors, in the brain. It is touted as an opioid analgesic that works on the central nervous system, which comprises of the brain and the spinal cord. 

Tramadol also works similarly to some antidepressants because it inhibits the reuptake of norepinephrine and serotonin. These brain chemicals are the ones used to transmit messages in-between nerve cells. As a pain message travels down a nerve, the cell’s end releases either of the two brain chemicals. The brain chemical gets into the gap in-between two nerve cells. 

When enough amounts of either serotonin or norepinephrine get to the second nerve cell, the cell’s receptors are activated enabling the message to proceed to its journey. The first cell fast absorbs any of the brain chemicals that are left in-between nerve cells. The absorption of the remaining brain chemicals is what we refer to as a “reuptake”.

What are the usual dosages for Tramadol?

If you are experiencing mild to moderately severe pain that lasts for a long period of time, take a 25 mg dose every morning if you are still new at the drug. Then, you can increase the dosage by 25 mg each time, as separate doses, after every three days to get to the 100 mg daily dosage. By then, you should take 25 mg four times a day. Then, you may increase your total daily dose by 50 mg according to what you, as the patient, can tolerate, every three days until you reach the 200 mg daily dosage. Upon reaching the 200 mg daily dosage, take 50 mg four times a day.

After titration, you maintain Tramadol intake by using dosages of 50 to 100 mg at a time every four to six hours. The dosage should not go over a maximum of 400 mg a day.

If you want to manage moderate to slighly severe chronic pain, you may require pain treatment round the clock for a long time.

If you are taking extended-release Tramadol, you should take an initial dose of 100 mg a day. Increments of 100 mg  may be used in titration every five days to relieve pain. The increments depend on your tolerability to the medication. The maximum dose for extended release tablets should only be 300 mg a day.

A different set of dosage requirements should be considered for patients who experience rapid analgesic effect, as well as for those who are experiencing more benefits than risks in terms of discontinuation. The dose should then be 50 to 100 mg every four to six hours. The total daily dosage should not go over 400 mg a day.More on Tramadol here

Geriatric Dosages

So, what is the geriatric dosage of Tramadol like? If you or someone who needs to take the drug is over 65 years old, you may need to use the dosing range’s lower end. At a more advanced age, the patient must be more cautious in using Tramadol. Geriatric patients are more likely to experience cardiac, hepatic or renal malfunction, with or without Tramadol. They are also more likely to be taking other medications alongside it.

For those who are over 75 years old, they can only take Tramadol at a maximum daily dosage of 300 mg that must be divided into several doses, as prescribed by their doctor. Again, the older you get, the more likely it would be for you to be treated for several health conditions at a time. 

Pediatric Dosages

Children must also take proper precautions when taking Tramadol. Children who are 16 years old or older may take an initial dose of Ryzolt at 100 mg once a day. Then, titration can be done by 100 mg increments after two to three days if the drug is still needed to control pain. The maximum daily dosage must be also 300 mg.

Warnings:

Patients should relay their full medical history, past and current drug and alcohol use, herbal medicine and vitamin use, and pregnancy/breastfeeding practices to their doctor. This way, they will be prescribed the right dose, which they should follow to the letter. This means that the patients should avoid alcohol and contraindicated drugs during treatment.  There will also be people who will not be recommended to take the drug because of a contraindicated medical condition. 
As with other drugs, Tramadol comes with all sorts of possible side effects. Overdose can be lethal. Extra care should also be given when the drug is being administered to people older than 65 years old or younger than 16 years old. 

Reasons Against Recreational Use

Recreational use of Tramadol can be very dangerous. At high doses, the drug can cause convulsions. Tramadol may also produce effects that are like those produced by codeine and similarly weak opioids due to the agonism of µ opioid receptors. Tramadol has a lower likeness to the receptor. So, the effects are not as intense as with other opiates. Also, Tramadol may discourage people from abusing it as it is more likely for people to experience dizziness, loss of appetite and nausea when using it instead of other opiates.